The Influence of Amyloid Precursor-Like Protein 2 and Invariant Chain on the Cell Surface Expression of Major Histocompatibility Complex Class I Molecules

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6 pages : PDF file ; cm.

Abstract: "In this study we extended previous findings on the effect of APLP2 on Kd to the human MHC class I molecules expressed by the breast tumor cell line MDA-MB 435S. In addition, we sought to determine the influence of down-regulating the expression of the endogenous invariant chain in the MDA-MB 435S cells. This will allow comparison of down-regulating invariant chain to previous results obtained with over-expression of invariant chain in breast tumor cells T47D and MCF-7."--page 2.

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  • The Influence of Amyloid Precursor-Like Protein 2 and Invariant Chain on the Cell Surface Expression of Major Histocompatibility Complex Class I Molecules
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  • 06/06/2024
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